个人简介
副研究员、博士生导师、医学博士。2020年加入重庆医科大学，主要从事本科生各层次病理学教学、临床病理诊断以及基础研究。任重庆医科大学病理诊断中心临床病理研究室副主任。主持国家级等科研项目5项。以第一作者及通讯作者发表国内外科技论文18篇，其中IF>10的8篇，2篇入选ESI高被引论文。参编著作1部，申请国家发明专利4项。指导学生参与校内外各项比赛获奖，4名研究生获“国家奖学金”，2名获得重庆市研究生科研创新项目资助。
教育背景及工作经历
2009.09-2014.07重庆医科大学本科
2014.09-2017.07重庆医科大学硕士研究生
2017.09--2020.06重庆医科大学博士研究生
2020.09—2022.12重庆医科大学助理研究员
2023.01至今重庆医科大学副研究员
学术兼职
中华医学会病理学分会科普工作组委员
中国微纳米技术学会高级会员
成都高新医学会临床病理分会委员
《Front. Bioeng. Biotechnol.》杂志客座主编，《VIEW》、《Regenerative Biomaterials》、《Nano Biomed. Eng.》、《Biomaterials Translational》青年编委，及多个SCI期刊审稿专家
奖项及荣誉
第四届全国暨际超声分子影像学术会议中青年论坛学术发言，二等奖
2021年重庆市病理学术年会青年论坛学术讲座，成就奖
重庆市医学会病理学分会2020年学术年会，优秀青年论文
第五届重庆市消化专业青年医生英语病例演讲比赛，第二名
重庆医科大学2021年双语教学比赛，3522浦京集团vip“三等奖”，校级“优秀奖”
作为指导老师指导学生获奖：2021年重庆医科大学大学生创新实验项目立项，2022年度重庆医科大学3522浦京集团vip“英耀计划二等奖”，第八届重庆市大学生创新创业大赛“校赛三等奖”，2022年度全国大学生“互联网+”院赛三等奖，2025年重庆市大学生创新方法大赛市赛一等奖（创新设计类）、二等奖（发明制作类）
主持科研项目
1.国家自然科学基金面上项目，82573329，“时-空”磁热化学动力凝胶递送内源性dsDNA激活AIM2-PANoptosis/免疫效应协同重塑TNBC微环境，2026/01-2029-12，49万，在研，主持
2.国家自然科学基金青年基金，82102909，产生非氧依赖性自由基的纳米梭用于乳腺癌分级靶向及光热/热动力联合治疗，2022/01-2024/12，30万元，结题，主持
3.重庆市自然科学基金面上项目，CSTB2022NSCQ-MSX0109,磁热免疫协同功能的产自由基生物凝胶用于乳腺癌微创治疗应用研究及机制探讨，2022/08-2025/07，10万元，结题，主持
4.重庆市教委科技项目青年项目，KJQN202300458，光热动力免疫凝胶调控肿瘤糖代谢诱导细胞焦亡用于乳腺癌微创治疗，2023/10-2026/09，4万元，在研，主持
5.重庆市教委科技项目青年项目，KJQN202500417，可注射磁性Xc-T转运体抑制剂介导铁死亡协同TAT增敏自噬共同崩解“肿瘤抗氧化效应”治疗TNBC，2025/7-2029/06，4万元，在研，主持
代表性论文、专利
1.Hui Yuan#, Xiongwu Li#, Muhua Yu, Youde Cao, Lingcheng Wu, Suyujie Shi, Yaying Yang*, Kexiao Yu*,Bing Liang*. Injectable SF-platform orchestrates GPX4-targetedferroptosis-autophagy-immunogenic circuit for overcoming oxidative resistance in triple-negative breast cancer. Theranostics, 2025; 15(17): 8757-8778 (IF:13.3).
2.Linyan Xiong,Bing Liang*, Kexiao Yu*. Magnetic hyperthermia in oncology: Nanomaterials-driven combinatorial strategies for synergistic therapeutic gains. Materials Today Bio, 2025, 33, 102070 (IF:10.2).
3.Zuying Li, Kexiao Yu, Youde Cao, Hui Yuan, Lingcheng Wu, Linyan Xiong, Yi Tang*,Bing Liang*. Breaking the Chains of Therapeutic Blockade: Pyroptosis-Induced Photothermal-Chemotherapy with Targeted Nanoprobes in Triple-Negative Breast Cancer. Biomaterials Research, 2025,15;29:0200. (IF:9.7).
4.Hang Zhou, Zongyuan He, Youde Cao, Lei Chu,Bing Liang*, Kexiao Yu*, Zhongliang Deng*. An injectable magnesium-loaded hydrogel releases hydrogen to promote osteoporotic bone repair via ROS scavenging and immunomodulation. Theranostics, 2024, 14(9), 3739-3759 (IF:13.3).
5.Quanhao He#, Bangxin Xiao#, Yiwen Tan#, Jun Wang#, Hao Tan, Canjie Peng,Bing Liang*, Youde Cao*, Mingzhao Xiao*. Integrated multicenter deep learning system for prognostic prediction in bladder cancer. NPJ Precision Oncology, 2024,8,233 (IF: 8.0).
6.Kexiao Yu#, Hang Zhou#, Yamei Xu, Youde Cao, Yuanyi Zheng*,Bing Liang*. Engineering a triple-functional magnetic gel driving mutually-synergistic mild hyperthermia-starvation therapy for osteosarcoma treatment and augmented bone regeneration. Journal of Nanobiotechnology, 2023, 21:201 (IF:10.6).
7.Bing Liang, Yijia Cao, Xinmei Wang, Hang Zhou, Mengna Wang, Youde Cao, Weizhong Lu, Kexiao Yu*. A “biomimetic bone-magnet” with suitable mechanical properties concurrently performs accurate target collection of nanoparticles for magnetothermally driven osteosarcoma thermo-chemotherapy. Materials and Design, 2023, 234, 112311. (IF:8.29).
8.Yamei Xu, Qiyuan Hu, Zongyun Wei, Yi Ou, Youde Cao, Hang Zhou, Mengna Wang, Kexiao Yu* andBing Liang*; Advanced polymer hydrogels that promote diabetic ulcer healing: mechanisms, classifications, and medical applications. Biomaterials Research, 2023, 27(1): 36. (IF:11.3).
9.Mengna Wang, Siyu Deng, Yijia Cao, Hang Zhou, Wei Wei, Kexiao Yu*, Youde Cao*,Bing Liang*; Injectable versatile liquid-solid transformation implants alliance checkpoint blockade for magnetothermal dynamic-immunotherapy. Materials Today Bio, 2022,16, 100442. (IF:10.761).
10.Bing Liang#, Bin Qiao#, Kexiao Yu, Jin Cao, Hang Zhou, Qinqin Jiang, Yixin Zhong, Youde Cao*, Zhigang Wang* and Yuanyi Zheng*; Mitochondrial Glutathione Depletion Nano-shuttles for Oxygen-Irrelevant Free Radicals Generation: A Cascaded Hierarchical Targeting and Theranostic Strategy Against Hypoxic Tumor. ACS Applied Materials & Interfaces, 2022, 14(11):13038-13055. (IF:10.304).
11.Hang Zhou#, Kexiao Yu#, Haitiao Jiang, Rui Deng, Lei Chu, Youde Cao, Yuanyi Zheng, Weizhong Lu, Zhongliang Deng*,Bing Liang*; A three in one strategy: injectable biomimetic porous hydrogels for accelerating bone regeneration by shape-adaptable scaffold, controllable magnesium release and enhanced osteogenic differentiation. Biomacromolecules, 2021, 22(11), 4552-4568. (作为封面文章出版，IF:6.988).
12.Hang Zhou#;Bing Liang#; Haitao Jiang; Zhongliang Deng*，Kexiao Yu*; Magnesium-based bio-materials as emerging agents for bone repair and regeneration: from mechanism to application, Journal of Magnesium and Alloys, 2021, 9(3), 779-804. (IF:11.813), ESI高被引论文.
13.Bing Liang#; Deyu Zuo#; Kexiao Yu#; Xiaojun Cai*; Bin Qiao; Rui Deng; Junsong Yang; Lei Chu; Zhongliang Deng; Yuanyi Zheng*; Guoqing Zuo*; Multifunctional bone cement for synergistic magnetic hyperthermia ablation and chemotherapy of osteosarcoma, Materials Science & Engineering C-Materials for Biological Applications, 2020, 108: 1-13. (IF:7.328).
14.Kexiao Yu#;Bing Liang#; Yuanyi Zheng*; Agata Exner; Michael Kolios; Tiantian Xu; Dajing Guo; Xiaojun Cai; Zhigang Wang; Haitao Ran; Lei Chu*; Zhongliang Deng*; PMMA-Fe3O4 for internal mechanical support and magnetic thermal ablation of bone tumors, Theranostics, 2019, 9(14): 4192-4207.（作为封面文章出版，IF:8.579）.
15.Bing Liang#; Kexiao Yu#; Yi Ling#; Micheal Kolios; Agata Exner; ZhigangWang; Bing Hu; Guoqing Zuo*; Yu Chen*; Yuanyi Zheng*; An artificially engineered “tumor bio-magnet” for collecting blood-circulating nanoparticles and magnetic hyperthermia, Biomaterials Science, 2019, 7(5): 1815-1824. (作为封面文章出版，IF:6.183）.
16.余柯晓，周航，梁冰；一种可控产氢促骨缺损修复水凝胶及其制备方法，专利号：ZL 2024 1 0633814.2，授权公告号：CN 118649285 B
17.唐毅，李祖莹，梁冰，余柯晓，袁慧，熊林燕，曹友德；一种浅表肿瘤靶向多模态诊疗纳米探针、制备方法与应用，申请号：202510051434.2
18. 梁冰，袁慧，杨雅莹，曹友德，余柯晓，吴凌澄；一种IMSFs水凝胶、铁死亡诱导系统、制备方法及应用，申请号：202510483971.4
19.余柯晓，袁慧，梁冰，余木华，熊林燕；TAT-beclin1、铁死亡诱导系统及应用；申请号：申请号：202510484208.3
